General Cell Lines and Cell Cultures
ATCC HPV type 18; purified plasmid DNA
HPV-18 purified plasmid DNA is a full-length clone of human papilloma virus type 18 that has been linearized at the unique EcoRI site (nt 2440) and cloned into the EcoRI site of pBR322.
Eurofins Discoverx PathHunter CHO-K1 CXCR7 (CMKOR1) β-Arrestin Cell Line, 2 vials. (93-0248C2)
The PathHunter CXCR7 (CMKOR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL12/SDF-1α) based activation of CXCR7 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR7 and EA-tagged β-Arrestin-2. Activation of CXCR7 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Enterobacter cloacae; Strain: 4118
Enterobacter cloacae strain 4118 was isolated from pus from a groin wound in California, United States. This strain is resistant to penicillins, carbapenems, and pipercillin-tazobactam and it is sensitive to aztreonam. The depositor states that this is the first serine carbapenemase described in the United States: the class A IMI-1, co-produced with TEM-1.
ATCC HCC1187; Breast Ductal Carcinoma; Human (Homo sapiens)
HCC1187 is a mammary gland epithelial cell that was isolated from a 41-year-old, White female patient with ductal carcinoma TNM Stage IIA, grade 3. The cell can be used in cancer research.
ATCC Chlamydia trachomatis; Serovar E; Strain: BOUR; Genomic DNA
Genomic DNA from Chlamydia trachomatis Serovar E strain BOUR was isolated from McCoy cells (ATCC CRL-1696) infected with Chlamydia trachomatis strain BOUR (ATCC VR-348B). This product was prepared using methods known to inactivate the infecting agent. The product can be used for PCR and other molecular applications. Source organism and host cells are also available through the ATCC Catalog.
ATCC Mino; Mantle Cell Lymphoma; Human (Homo sapiens)
Mino cells are lymphoblasts isolated from the peripheral blood of a 64-year-old, White male with mantle cell lymphoma. It can be used for immunology research.
Discovery Life Sciences Esophageal Cncr Mutation PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Discovery Life Sciences Gastric Ca Prog/Ref/Rel PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Discovery Life Sciences Head Neck Ca Active Tx PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Discovery Life Sciences Breast Ca TNBC Tx Naive PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
Biochain Institute Inc Paraffin Tissue Section - Human Appendix Tumor: Adenocarcinoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx Ready-to-Assay FFA1/GPR40 Free Fatty Acid Receptor Frozen Cells, 2 Vials of Cells. (HTS038LRTA)
The Ready-to-Assay FFA1/GPR40 Free Fatty Acid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. free fatty acids) based activation of FFAR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FFAR1 alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of FFAR1, the resulting calcium activity can be assayed in either detection mode. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
iXCells Biotechnologies Peripheral Blood Mononuclear Cells (PBMCs), 10M
Peripheral Blood Mononuclear Cells (PBMCs) is any blood cell with a single nucleus. PBMCs consist of lymphocytes (T, B and NK cells), monocytes and dendritic cells. iXCells Biotechnologies offers PBMCs from the human peripheral blood of individual healthy donors. These PBMCs are purified from peripheral blood using ficoll gradient centrifugation.
iXCells Biotechnologies Human Hepatic Stellate Cells- Adult (HHSC)
iXCells Biotechnologies provides high quality Human Hepatic Stellate Cells (HHSC), which are isolated from adult human liver and cryopreserved with >1 million cells in each vial. Each vial is sufficient to seed on four 10 cm dishes, and cells will be ready in 5~6 days to be passaged at 1:3 ratio. HUSMC express Desmin and GFAP, and are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fung. HUSMC can further expand for 2-3 population doublings in¿Stellate Cell Growth Medium¿under the condition suggested by iXCells Biotechnologies.
Eurofins Discoverx PathHunter CHO-K1 GPR171 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0415C2A)
The PathHunter GPR171 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR171 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR171 and EA-tagged β-Arrestin-2. Activation of GPR171 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.